What combination is commonly found in Suboxone?

Suboxone is a medication specifically designed for the treatment of opioid addiction and is a combination of buprenorphine and naloxone. Buprenorphine is a partial opioid agonist that helps relieve pain and reduce cravings for opioids while also minimizing withdrawal symptoms without producing the same euphoric high associated with full opioid agonists. This helps patients transition away from stronger opioids.

The addition of naloxone serves a critical purpose. Naloxone is an opioid antagonist that can precipitate withdrawal symptoms if the medication is misused by injecting it. Therefore, its inclusion is intended to deter misuse and provides a safety mechanism. When taken as prescribed, naloxone has minimal effects because buprenorphine occupies the opioid receptors in a way that makes naloxone ineffective, but it is a deterrent against potential abuse.

In contrast, the other options consist of different combinations of medications that are not found in Suboxone and serve different purposes in pain management and addiction treatment.